|
gptkbp:instanceOf
|
gptkb:disease
leukemia
rare cancer
|
|
gptkbp:abbreviation
|
gptkb:HCL
|
|
gptkbp:affects
|
gptkb:B_lymphocytes
spleen
bone marrow
|
|
gptkbp:cause
|
fatigue
splenomegaly
infections
easy bruising
pancytopenia
|
|
gptkbp:diagnosedBy
|
bone marrow biopsy
blood smear
flow cytometry
|
|
gptkbp:firstDescribed
|
1958
|
|
gptkbp:hasOrphanetID
|
ORPHA:524
|
|
gptkbp:hasType
|
hairy cells
|
|
gptkbp:hasTypicalAgeOfOnset
|
middle-aged adults
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
hairy cell leukemia
|
|
gptkbp:ICD-10_code
|
C91.4
|
|
gptkbp:MeSH_ID
|
D006393
|
|
gptkbp:mutationAssociatedWith
|
gptkb:BRAF_V600E
|
|
gptkbp:namedFor
|
gptkb:Bertha_Bouroncle
|
|
gptkbp:OMIM
|
235730
|
|
gptkbp:prevalence
|
rare
|
|
gptkbp:prognosis
|
generally good with treatment
|
|
gptkbp:subspecies
|
gptkb:chronic_lymphoid_leukemia
|
|
gptkbp:symptom
|
gptkb:anemia
neutropenia
thrombocytopenia
|
|
gptkbp:treatment
|
gptkb:rituximab
gptkb:cladribine
gptkb:pentostatin
interferon alpha
|
|
gptkbp:bfsParent
|
gptkb:B-Raf_protein
gptkb:7q34_(BRAF)
gptkb:BRAF_V600E
gptkb:INTRON_A
gptkb:Cladribine
|
|
gptkbp:bfsLayer
|
6
|