Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:beta-catenin
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:encodedBy |
gptkb:CTNNB1_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
gptkb:Wnt_signaling_pathway
cell adhesion |
| https://www.w3.org/2000/01/rdf-schema#label |
catenin beta-1
|
| gptkbp:interactsWith |
gptkb:APC_protein
gptkb:TCF/LEF_transcription_factors gptkb:cadherins |
| gptkbp:involvedIn |
embryonic development
tumorigenesis |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_3p22.1
|
| gptkbp:location |
gptkb:cell_membrane
gptkb:nucleus gptkb:cytoplasm |
| gptkbp:molecularWeight |
~85 kDa
|
| gptkbp:mutationAssociatedWith |
colorectal cancer
hepatocellular carcinoma |
| gptkbp:postTranslationalModification |
phosphorylation
ubiquitination |
| gptkbp:regulates |
cell differentiation
cell proliferation gene transcription |
| gptkbp:structure |
contains armadillo repeats
|
| gptkbp:UniProtID |
gptkb:P35222
|
| gptkbp:bfsParent |
gptkb:β-catenin
|
| gptkbp:bfsLayer |
7
|