breast cancer type 1 susceptibility protein
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:BRCA1
|
| gptkbp:associatedWith |
gptkb:hereditary_breast_cancer
hereditary ovarian cancer |
| gptkbp:discoveredBy |
gptkb:Mary-Claire_King
|
| gptkbp:discoveredIn |
1990
|
| gptkbp:encodedBy |
gptkb:BRCA1_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
DNA repair
tumor suppression |
| https://www.w3.org/2000/01/rdf-schema#label |
breast cancer type 1 susceptibility protein
|
| gptkbp:interactsWith |
gptkb:BARD1
gptkb:PALB2 gptkb:RAD51 |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_17
|
| gptkbp:molecularWeight |
220 kDa
|
| gptkbp:mutationAssociatedWith |
increased cancer risk
|
| gptkbp:OMIM |
113705
|
| gptkbp:PDB |
gptkb:1JM7
|
| gptkbp:subcellularLocation |
gptkb:nucleus
|
| gptkbp:UniProtID |
P38398
|
| gptkbp:bfsParent |
gptkb:ENSG00000145675
|
| gptkbp:bfsLayer |
6
|