alpha-2-macroglobulin receptor
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:LRP1
low density lipoprotein receptor-related protein 1 |
| gptkbp:binds |
gptkb:tissue_plasminogen_activator
gptkb:apolipoprotein_E alpha-2-macroglobulin-protease complexes |
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000123384
|
| gptkbp:expressedIn |
brain
liver macrophages smooth muscle cells |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
endocytosis of various ligands
clearance of protease-inhibitor complexes |
| gptkbp:gene |
gptkb:LRP1
|
| https://www.w3.org/2000/01/rdf-schema#label |
alpha-2-macroglobulin receptor
|
| gptkbp:interactsWith |
gptkb:tissue_factor_pathway_inhibitor
gptkb:amyloid_precursor_protein reelin |
| gptkbp:locatedOnChromosome |
12q13.3
|
| gptkbp:molecularWeight |
~600 kDa
|
| gptkbp:OMIM |
107770
|
| gptkbp:relatedTo |
gptkb:Alzheimer's_disease
atherosclerosis |
| gptkbp:structure |
single-pass type I membrane protein
|
| gptkbp:UniProtID |
gptkb:Q07954
|
| gptkbp:bfsParent |
gptkb:LRP1
|
| gptkbp:bfsLayer |
7
|