|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:YY1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
developmental disorders
|
|
gptkbp:binds
|
gptkb:gene
|
|
gptkbp:discoveredBy
|
Shi et al.
|
|
gptkbp:discoveredIn
|
1991
|
|
gptkbp:encodedBy
|
gptkb:YY1_gene
|
|
gptkbp:Entrez_Gene_ID
|
7528
ENSG00000100811
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:hasDNAConsensusSequence
|
5'-CCATNTT-3'
|
|
gptkbp:hasNuclearLocalizationSignal
|
yes
|
|
gptkbp:hasRole
|
gptkb:X-chromosome_inactivation
DNA repair
cell cycle regulation
chromatin remodeling
|
|
gptkbp:hasZincFingerDomain
|
yes
|
|
gptkbp:HGNC_ID
|
12852
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Yin Yang 1
|
|
gptkbp:interactsWith
|
gptkb:SP1
gptkb:c-Myc
gptkb:E2F
gptkb:Polycomb_group_proteins
HDACs
GATA proteins
p300/CBP
|
|
gptkbp:involvedIn
|
apoptosis
cell proliferation
embryogenesis
cellular differentiation
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_14
|
|
gptkbp:molecularWeight
|
~65 kDa
|
|
gptkbp:OMIM
|
600013
|
|
gptkbp:orthologInMouse
|
Yy1
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
acetylation
|
|
gptkbp:regulates
|
gene expression
transcription
oncogenes
tumor suppressor genes
immunoglobulin gene expression
|
|
gptkbp:UniProtID
|
P25490
|
|
gptkbp:bfsParent
|
gptkb:YY1
|
|
gptkbp:bfsLayer
|
8
|