Vesicle-associated membrane protein

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:abbreviation	gptkb:VAMP
gptkbp:associatedWith	tetanus botulism
gptkbp:biologicalProcess	membrane fusion SNARE binding syntaxin binding
gptkbp:cellularComponent	gptkb:plasma_membrane integral component of membrane vesicle membrane
gptkbp:component	gptkb:SNARE_complex
gptkbp:discoveredBy	gptkb:James_E._Rothman
gptkbp:function	mediates vesicle fusion
gptkbp:GO_term	GO:0005484 GO:0006887 GO:0016192
gptkbp:involvedIn	neurotransmitter release endocytosis exocytosis
gptkbp:location	synaptic vesicle membrane endosome membrane
gptkbp:member	gptkb:VAMP1 gptkb:VAMP2 gptkb:VAMP3 gptkb:VAMP4 gptkb:VAMP5 gptkb:VAMP7 gptkb:VAMP8
gptkbp:molecularWeight	~13 kDa (VAMP2)
gptkbp:orthologIn	gptkb:Mus_musculus gptkb:Homo_sapiens gptkb:Drosophila_melanogaster
gptkbp:proteinFamily	gptkb:VAMP_gene_family
gptkbp:relatedTo	gptkb:SNAP-25 gptkb:syntaxin gptkb:synaptobrevin
gptkbp:structure	cytoplasmic domain single transmembrane domain SNARE motif
gptkbp:target	gptkb:botulinum_toxin_B gptkb:botulinum_toxin_D gptkb:botulinum_toxin_F gptkb:tetanus_toxin
gptkbp:UniProtID	gptkb:O95180_(VAMP7) gptkb:O95183_(VAMP4) gptkb:P63027_(VAMP2) P23763 (VAMP1) Q15836 (VAMP3) Q9BV40 (VAMP5) Q9BV40 (VAMP8)
gptkbp:bfsParent	gptkb:VAMP
gptkbp:bfsLayer	6
https://www.w3.org/2000/01/rdf-schema#label	Vesicle-associated membrane protein