|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:endobrevin
|
|
gptkbp:associatedWith
|
gptkb:diabetes_mellitus
bleeding disorders
immune disorders
|
|
gptkbp:cellularComponent
|
gptkb:lysosome
gptkb:endosome
gptkb:plasma_membrane
vesicle membrane
|
|
gptkbp:discoveredBy
|
Wong et al.
|
|
gptkbp:discoveredIn
|
1998
|
|
gptkbp:encodedBy
|
gptkb:VAMP8_gene
|
|
gptkbp:Entrez_Gene_ID
|
8673
ENSG00000134207
|
|
gptkbp:fullName
|
gptkb:Vesicle-associated_membrane_protein_8
|
|
gptkbp:function
|
involved in endocytosis
SNARE protein involved in vesicle fusion
regulates exocytosis
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
12644
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
VAMP8
|
|
gptkbp:interactsWith
|
gptkb:SNAP23
gptkb:SNAP25
gptkb:VTI1B
gptkb:syntaxin_7
gptkb:syntaxin_8
|
|
gptkbp:involvedIn
|
insulin secretion
mast cell degranulation
platelet granule secretion
regulated exocytosis in immune cells
|
|
gptkbp:length
|
104 amino acids
|
|
gptkbp:locatedOnChromosome
|
2p11.2
|
|
gptkbp:molecularWeight
|
11.3 kDa
|
|
gptkbp:OMIM
|
603177
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Danio_rerio
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:proteinFamily
|
gptkb:SNARE_family
|
|
gptkbp:tissue_specificity
|
gptkb:cancer
brain
pancreas
platelets
immune cells
|
|
gptkbp:UniProtID
|
O95070
|
|
gptkbp:bfsParent
|
gptkb:VAMP
|
|
gptkbp:bfsLayer
|
6
|