O95180 (VAMP7)

GPTKB entity

Statements (54)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:TI-VAMP
gptkb:Vesicle-associated_membrane_protein_7
gptkbp:associatedWith neurodevelopmental disorders
gptkbp:biologicalProcess endocytosis
exocytosis
vesicle-mediated transport
SNARE binding
syntaxin binding
gptkbp:database gptkb:GeneCards
gptkb:NCBI_Gene
gptkb:HGNC
gptkb:UniProt
gptkb:Ensembl
gptkbp:domain Longin domain
SNARE domain
gptkbp:Entrez_Gene_ID gptkb:ENSG00000139190
10099
gptkbp:expressedIn ubiquitous
high in brain
high in testis
gptkbp:function involved in vesicle fusion
SNARE complex component
gptkbp:gene gptkb:VAMP7
gptkbp:GO GO:0005484 (SNARE binding)
GO:0006886 (intracellular protein transport)
GO:0016192 (vesicle-mediated transport)
gptkbp:hasIsoform VAMP7-1
VAMP7-2
gptkbp:HGNC_ID 12644
https://www.w3.org/2000/01/rdf-schema#label O95180 (VAMP7)
gptkbp:interactsWith gptkb:STX8
gptkb:VTI1B
STX7
gptkbp:length 220 amino acids
gptkbp:locatedOnChromosome 1q24.2
gptkbp:location gptkb:cell_membrane
gptkb:cytoplasm
gptkbp:molecularWeight 24.8 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologIn Mus musculus VAMP7
Rattus norvegicus VAMP7
gptkbp:pathway Endocytosis
SNARE interactions in vesicular transport
gptkbp:postTranslationalModification phosphorylation
ubiquitination
gptkbp:proteinFamily gptkb:SNARE_family
gptkbp:RefSeq NP_003370.1
gptkbp:sequenceStatus reviewed
gptkbp:subunit part of SNARE complex
gptkbp:transmembraneDomains residues 187-207
gptkbp:UniProtID O95180
gptkbp:bfsParent gptkb:Vesicle-associated_membrane_protein
gptkbp:bfsLayer 7