|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:SYBL1
gptkb:TIVAMP
|
|
gptkbp:alternativeName
|
gptkb:TI-VAMP
gptkb:Tetanus-insensitive_VAMP
gptkb:vesicle-associated_membrane_protein_7
|
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gptkbp:discoveredBy
|
researchers studying SNARE proteins
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gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000139190
10099
|
|
gptkbp:expressedIn
|
brain
various tissues
immune cells
|
|
gptkbp:firstDescribed
|
1998
|
|
gptkbp:fullName
|
gptkb:Vesicle-associated_membrane_protein_7
|
|
gptkbp:function
|
involved in vesicle trafficking
mediates fusion of vesicles with target membranes
|
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gptkbp:gene
|
gptkb:VAMP7
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
GO:0005484 (SNARE binding)
GO:0006886 (intracellular protein transport)
GO:0006897 (endocytosis)
GO:0006904 (vesicle fusion)
|
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gptkbp:HGNC_ID
|
12647
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
VAMP7
|
|
gptkbp:interactsWith
|
gptkb:SNAP23
gptkb:SNAP29
gptkb:STX8
gptkb:VTI1B
gptkb:syntaxin_7
|
|
gptkbp:length
|
220 amino acids
|
|
gptkbp:locatedOnChromosome
|
1
|
|
gptkbp:location
|
1q32.2
|
|
gptkbp:molecularWeight
|
~25 kDa
|
|
gptkbp:mutationAssociatedWith
|
neurological disorders
|
|
gptkbp:OMIM
|
604876
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Vamp7
rat Vamp7
|
|
gptkbp:proteinFamily
|
gptkb:SNARE
|
|
gptkbp:RefSeq
|
NM_003945
NP_003936
|
|
gptkbp:relatedTo
|
autophagy
endocytosis
exocytosis
lysosomal trafficking
|
|
gptkbp:subcellularLocation
|
lysosome membrane
endosome membrane
vesicle membrane
|
|
gptkbp:UniProtID
|
O95183
|
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gptkbp:bfsParent
|
gptkb:VAMP
|
|
gptkbp:bfsLayer
|
6
|