Statements (33)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:associatedWith |
gptkb:Parkinson's_disease
gptkb:depression schizophrenia |
gptkbp:encodedBy |
gptkb:SLC18A1
gptkb:SLC18A2 |
gptkbp:foundIn |
neurons
neuroendocrine cells |
gptkbp:fullName |
gptkb:Vesicular_monoamine_transporter
|
gptkbp:function |
transports monoamines into synaptic vesicles
|
gptkbp:hasIsoform |
gptkb:VMAT1
gptkb:VMAT2 |
https://www.w3.org/2000/01/rdf-schema#label |
VMAT
|
gptkbp:inhibitedBy |
gptkb:tetrabenazine
gptkb:reserpine amphetamine |
gptkbp:location |
synaptic vesicle membrane
|
gptkbp:molecularWeight |
~55 kDa
|
gptkbp:orthologIn |
gptkb:C._elegans
insects mammals |
gptkbp:powerSource |
proton gradient
|
gptkbp:proteinFamily |
gptkb:SLC18_family
|
gptkbp:role |
neurotransmitter release
neurotransmitter storage |
gptkbp:structure |
12 transmembrane domains
|
gptkbp:transportation |
gptkb:histamine
dopamine norepinephrine serotonin epinephrine |
gptkbp:bfsParent |
gptkb:Vladimir_Matyushenko
|
gptkbp:bfsLayer |
6
|