Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:receptor_tyrosine_kinase
gptkb:protein |
| gptkbp:alternativeName |
gptkb:FLT1
gptkb:Fms-like_tyrosine_kinase_1 |
| gptkbp:binds |
gptkb:VEGF-B
placenta growth factor (PlGF) vascular endothelial growth factor A (VEGF-A) |
| gptkbp:biologicalProcess |
receptor activity
protein tyrosine kinase activity |
| gptkbp:discoveredBy |
gptkb:Napoleone_Ferrara
|
| gptkbp:discoveredIn |
1992
|
| gptkbp:encodedBy |
gptkb:FLT1_gene
|
| gptkbp:expressedIn |
macrophages
endothelial cells monocytes |
| gptkbp:function |
regulation of angiogenesis
endothelial cell proliferation vascular permeability |
| gptkbp:hasIsoform |
soluble VEGFR-1 (sFlt-1)
|
| https://www.w3.org/2000/01/rdf-schema#label |
VEGFR-1 (Flt-1)
|
| gptkbp:locatedIn |
gptkb:cell_membrane
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_13q12
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:significance |
gptkb:cancer
preeclampsia |
| gptkbp:UniProtID |
P17948
|
| gptkbp:bfsParent |
gptkb:placental_growth_factor_(PlGF)
|
| gptkbp:bfsLayer |
7
|