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gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:endobrevin
vesicle-associated membrane protein 8
|
|
gptkbp:associatedWith
|
immune response
endocytosis
exocytosis
platelet degranulation
|
|
gptkbp:discoveredBy
|
researchers in the late 1990s
|
|
gptkbp:encodes
|
VAMP8 protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:VAMP8
8673
ENSG00000115944
|
|
gptkbp:expressedIn
|
various tissues
pancreas
platelets
immune cells
|
|
gptkbp:fullName
|
vesicle-associated membrane protein 8
|
|
gptkbp:function
|
involved in vesicle trafficking
mediates vesicle fusion
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:12647
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
VAMP8 gene
|
|
gptkbp:interactsWith
|
gptkb:SNAP23
other SNARE proteins
syntaxin proteins
|
|
gptkbp:length
|
4 exons
100 amino acids
|
|
gptkbp:locatedOnChromosome
|
chromosome 2
2p11.2
|
|
gptkbp:mutationAssociatedWith
|
gptkb:diabetes
inflammatory diseases
|
|
gptkbp:OMIM
|
603177
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Vamp8
|
|
gptkbp:pathway
|
immune system pathway
SNARE interactions in vesicular transport
insulin secretion pathway
|
|
gptkbp:product
|
integral membrane protein
|
|
gptkbp:proteinFamily
|
gptkb:SNARE_family
|
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gptkbp:RefSeq
|
NM_014398
|
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gptkbp:subcellularLocation
|
gptkb:lysosome
gptkb:endosome
gptkb:plasma_membrane
vesicle membrane
|
|
gptkbp:UniProtID
|
O95070
|
|
gptkbp:bfsParent
|
gptkb:VAMP8
|
|
gptkbp:bfsLayer
|
7
|