|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
Basic fibroblast growth factor
FGF-2
bFGF
|
|
gptkbp:associatedWith
|
gptkb:Melanoma
gptkb:Glioblastoma
Atherosclerosis
Breast cancer
|
|
gptkbp:biologicalProcess
|
cell proliferation
angiogenesis
growth factor activity
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
extracellular region
|
|
gptkbp:disulfideBond
|
Yes
|
|
gptkbp:function
|
Involved in wound healing
Promotes angiogenesis
Stimulates proliferation of a wide variety of cells
|
|
gptkbp:gene
|
gptkb:FGF2
|
|
gptkbp:hasIsoform
|
5
|
|
gptkbp:HGNC_ID
|
HGNC:3666
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
UniProt: P09082
|
|
gptkbp:KEGGID
|
hsa:2247
|
|
gptkbp:lastAnnotationUpdate
|
2021-11-17
|
|
gptkbp:latestReleaseVersion
|
1988-11-01
|
|
gptkbp:locatedOnChromosome
|
4q27-q31
|
|
gptkbp:mass
|
31 kDa
|
|
gptkbp:name
|
FGF2_HUMAN
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:Ras_signaling_pathway
|
|
gptkbp:PDB
|
gptkb:1BLA
1BFG
4OEG
|
|
gptkbp:postTranslationalModification
|
N-terminal processed
Phosphorylated
|
|
gptkbp:Reactome
|
R-HSA-5654695
|
|
gptkbp:recommendation
|
Fibroblast growth factor 2
|
|
gptkbp:RefSeq
|
NP_001997.3
|
|
gptkbp:sequence
|
288
|
|
gptkbp:sequenceStatus
|
Reviewed
|
|
gptkbp:signalPeptide
|
No
|
|
gptkbp:subcellularLocation
|
gptkb:Nucleus
gptkb:Cytoplasm
Secreted
|
|
gptkbp:tissue_specificity
|
Widely expressed
|
|
gptkbp:UniGene
|
Hs.654682
|
|
gptkbp:UniProtID
|
ENSP00000349449
|
|
gptkbp:bfsParent
|
gptkb:FBgn0001624
|
|
gptkbp:bfsLayer
|
8
|