Ubiquitin-conjugating enzyme E2 L3

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:UBCH7 UBC7
gptkbp:associatedWith	gptkb:systemic_lupus_erythematosus gptkb:Crohn's_disease autoimmune diseases rheumatoid arthritis
gptkbp:biologicalProcess	ubiquitin-conjugating enzyme activity
gptkbp:cellularComponent	gptkb:nucleus gptkb:cytoplasm
gptkbp:conservedIn	eukaryotes
gptkbp:discoveredIn	1996
gptkbp:encodedBy	UBE2L3 gene
gptkbp:Entrez_Gene_ID	7336 ENSG00000136143
gptkbp:foundIn	gptkb:Homo_sapiens
gptkbp:function	ubiquitin-protein transferase activity
gptkbp:HGNC_ID	12473
gptkbp:interactsWith	gptkb:E6AP gptkb:NEDD4 gptkb:SMURF2 gptkb:WWP1 gptkb:UBE3A
gptkbp:involvedIn	ubiquitin-dependent protein catabolic process
gptkbp:length	154 amino acids
gptkbp:locatedOnChromosome	gptkb:22q11.21
gptkbp:mass	17 kDa
gptkbp:OMIM	603697
gptkbp:orthologIn	gptkb:Mus_musculus gptkb:Rattus_norvegicus
gptkbp:participatedIn	protein ubiquitination
gptkbp:PDB	1IYF 2C4P
gptkbp:postTranslationalModification	phosphorylation ubiquitination
gptkbp:RefSeq	NP_003338.1
gptkbp:reviewedBy	gptkb:UniProtKB/Swiss-Prot
gptkbp:structure	contains UBC domain
gptkbp:UniProtID	P68036
gptkbp:bfsParent	gptkb:UBE2L3
gptkbp:bfsLayer	8
http://www.w3.org/2000/01/rdf-schema#label	Ubiquitin-conjugating enzyme E2 L3