Ubiquitin-conjugating enzyme E2 L3

URI: https://gptkb.org/entity/Ubiquitin-conjugating_enzyme_E2_L3
GPTKB entity
Statements (42)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:UBCH7
UBC7
gptkbp:associatedWith gptkb:systemic_lupus_erythematosus
gptkb:Crohn's_disease
autoimmune diseases
rheumatoid arthritis
gptkbp:biologicalProcess ubiquitin-conjugating enzyme activity
gptkbp:cellularComponent gptkb:nucleus
gptkb:cytoplasm
gptkbp:conservedIn eukaryotes
gptkbp:discoveredIn 1996
gptkbp:encodedBy UBE2L3 gene
gptkbp:Entrez_Gene_ID 7336
ENSG00000136143
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function ubiquitin-protein transferase activity
gptkbp:HGNC_ID 12473
https://www.w3.org/2000/01/rdf-schema#label Ubiquitin-conjugating enzyme E2 L3
gptkbp:interactsWith gptkb:E6AP
gptkb:NEDD4
gptkb:SMURF2
gptkb:WWP1
gptkb:UBE3A
gptkbp:involvedIn ubiquitin-dependent protein catabolic process
gptkbp:length 154 amino acids
gptkbp:locatedOnChromosome gptkb:22q11.21
gptkbp:mass 17 kDa
gptkbp:OMIM 603697
gptkbp:orthologIn gptkb:Mus_musculus
gptkb:Rattus_norvegicus
gptkbp:participatedIn protein ubiquitination
gptkbp:PDB 1IYF
2C4P
gptkbp:postTranslationalModification phosphorylation
ubiquitination
gptkbp:RefSeq NP_003338.1
gptkbp:reviewedBy gptkb:UniProtKB/Swiss-Prot
gptkbp:structure contains UBC domain
gptkbp:UniProtID P68036
gptkbp:bfsParent gptkb:UBE2L3
gptkbp:bfsLayer 8