Tyrosine-protein phosphatase non-receptor type 3

URI: https://gptkb.org/entity/Tyrosine-protein_phosphatase_non-receptor_type_3
GPTKB entity
Statements (47)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:PTPH1
gptkb:Protein_tyrosine_phosphatase_H1
PTP H1
gptkbp:associatedWith gptkb:cancer
gptkbp:biologicalProcess signal transduction
cell cycle regulation
dephosphorylation
gptkbp:domain gptkb:protein_tyrosine_phosphatase_domain
PDZ domain
gptkbp:Entrez_Gene_ID GC09P137073
gptkbp:enzymeCommissionNumber 3.1.3.48
gptkbp:expressedIn gptkb:cancer
gptkb:placenta
gptkb:testis
brain
liver
gptkbp:family gptkb:protein_tyrosine_phosphatase_family
gptkbp:function signal transduction
protein tyrosine phosphatase activity
gptkbp:gene gptkb:PTPN3
gptkbp:HGNC_ID 9640
https://www.w3.org/2000/01/rdf-schema#label Tyrosine-protein phosphatase non-receptor type 3
gptkbp:interactsWith gptkb:14-3-3_proteins
gptkb:TGF-beta_receptor_type_I
gptkb:p97/VCP
gptkbp:length 913 amino acids
gptkbp:locatedOnChromosome chromosome 9q34.3
gptkbp:location gptkb:cytoplasm
gptkbp:molecularWeight 110 kDa
gptkbp:OMIM 176882
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse gptkb:Ptpn3
gptkbp:postTranslationalModification phosphorylation
ubiquitination
gptkbp:RefSeq NP_002818.2
gptkbp:regulates cell differentiation
cell growth
mitotic cell cycle
gptkbp:structure contains one PDZ domain
contains one PTPc domain
gptkbp:subcellularLocation gptkb:cytoplasm
membrane-associated
gptkbp:subfamily non-receptor type protein tyrosine phosphatases
gptkbp:UniProtID Q12923
gptkbp:bfsParent gptkb:PTPN3
gptkbp:bfsLayer 7