|
gptkbp:instanceOf
|
gptkb:cell_membrane
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:CD71
|
|
gptkbp:binds
|
gptkb:transferrin
|
|
gptkbp:discoveredBy
|
Ian M. Trowbridge
|
|
gptkbp:encodedBy
|
TFRC gene
|
|
gptkbp:expressedIn
|
gptkb:breast
gptkb:cervix
gptkb:endometrium
gptkb:fallopian_tube
gptkb:gallbladder
gptkb:cancer
gptkb:hepatocytes
gptkb:melanocytes
gptkb:bone
gptkb:skin
gptkb:pituitary_gland
gptkb:Langerhans_cells
gptkb:skeletal_muscle
gptkb:adrenal_gland
gptkb:kidney
gptkb:placenta
gptkb:prostate
gptkb:small_intestine
gptkb:testis
gptkb:thymus
gptkb:keratinocytes
gptkb:osteoclasts
gptkb:urinary_bladder
gptkb:germ_cells
gptkb:microglia
gptkb:megakaryocytes
gptkb:spermatogonia
gptkb:oligodendrocytes
brain
eye
heart
retina
liver
collagen
spleen
tonsil
adipose tissue
bone marrow
colon
esophagus
lymph node
pancreas
parathyroid gland
salivary gland
stomach
thyroid gland
uterus
neurons
dendritic cells
macrophages
appendix
endothelial cells
fibroblasts
stromal cells
astrocytes
rectum
monocytes
epithelial cells
adipocytes
lymphocytes
granulocytes
chondrocytes
erythroid precursors
osteoblasts
smooth muscle cells
proliferating cells
pancreatic islet cells
renal tubular cells
oocytes
granulosa cells
theca cells
placental trophoblasts
osteocytes
skeletal muscle cells
cytotrophoblasts
luteal cells
myocytes
syncytiotrophoblasts
trophoblasts
|
|
gptkbp:foundIn
|
gptkb:cell_membrane
|
|
gptkbp:function
|
iron uptake
|
|
gptkbp:HGNC_ID
|
TFRC
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Transferrin receptor
|
|
gptkbp:internalization
|
clathrin-mediated endocytosis
|
|
gptkbp:locatedOnChromosome
|
chromosome 3q29
|
|
gptkbp:molecularWeight
|
~85 kDa
|
|
gptkbp:OMIM
|
190010
|
|
gptkbp:PDB
|
1CX8
|
|
gptkbp:significance
|
target for cancer therapy
marker for cell proliferation
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:UniProtID
|
P02786
|
|
gptkbp:bfsParent
|
gptkb:Transferrin
|
|
gptkbp:bfsLayer
|
7
|