|
gptkbp:instanceOf
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gptkb:cell_membrane
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:CD71
|
|
gptkbp:binds
|
gptkb:transferrin
|
|
gptkbp:discoveredBy
|
Ian M. Trowbridge
|
|
gptkbp:encodedBy
|
TFRC gene
|
|
gptkbp:expressedIn
|
gptkb:breast
gptkb:cervix
gptkb:endometrium
gptkb:fallopian_tube
gptkb:gallbladder
gptkb:adipose_tissue
gptkb:eye
gptkb:cancer
gptkb:hepatocytes
gptkb:melanocytes
gptkb:bone
gptkb:skin
gptkb:pituitary_gland
gptkb:Langerhans_cells
gptkb:collagen
gptkb:skeletal_muscle
gptkb:adrenal_gland
gptkb:kidney
gptkb:placenta
gptkb:prostate
gptkb:small_intestine
gptkb:testis
gptkb:thymus
gptkb:keratinocytes
gptkb:osteoclasts
gptkb:urinary_bladder
gptkb:germ_cells
gptkb:neurons
gptkb:microglia
gptkb:appendix
gptkb:megakaryocytes
gptkb:spermatogonia
gptkb:lymph_node
gptkb:salivary_gland
gptkb:oligodendrocytes
brain
heart
retina
liver
spleen
tonsil
bone marrow
colon
esophagus
pancreas
parathyroid gland
stomach
thyroid gland
uterus
dendritic cells
macrophages
endothelial cells
fibroblasts
stromal cells
astrocytes
rectum
monocytes
epithelial cells
adipocytes
lymphocytes
granulocytes
chondrocytes
erythroid precursors
osteoblasts
smooth muscle cells
proliferating cells
pancreatic islet cells
renal tubular cells
oocytes
granulosa cells
theca cells
placental trophoblasts
osteocytes
skeletal muscle cells
cytotrophoblasts
luteal cells
myocytes
syncytiotrophoblasts
trophoblasts
|
|
gptkbp:foundIn
|
gptkb:cell_membrane
|
|
gptkbp:function
|
iron uptake
|
|
gptkbp:HGNC_ID
|
TFRC
|
|
gptkbp:internalization
|
clathrin-mediated endocytosis
|
|
gptkbp:locatedOnChromosome
|
chromosome 3q29
|
|
gptkbp:molecularWeight
|
~85 kDa
|
|
gptkbp:OMIM
|
190010
|
|
gptkbp:PDB
|
1CX8
|
|
gptkbp:significance
|
target for cancer therapy
marker for cell proliferation
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:UniProtID
|
P02786
|
|
gptkbp:bfsParent
|
gptkb:Transferrin
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Transferrin receptor
|