|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:NTRK1
|
|
gptkbp:associatedWith
|
gptkb:nerve_growth_factor_receptor
|
|
gptkbp:discoveredBy
|
gptkb:Mariano_Barbacid
|
|
gptkbp:discoveredIn
|
1986
|
|
gptkbp:encodes
|
gptkb:neurotrophic_receptor_tyrosine_kinase_1
|
|
gptkbp:Entrez_Gene_ID
|
4914
ENSG00000198400
|
|
gptkbp:expressedIn
|
gptkb:nervous_system
|
|
gptkbp:HGNC_ID
|
8031
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TRK A
|
|
gptkbp:involvedIn
|
cell survival
signal transduction
neuronal differentiation
|
|
gptkbp:ligand
|
gptkb:nerve_growth_factor_(NGF)
|
|
gptkbp:locatedOnChromosome
|
chromosome 1
|
|
gptkbp:memberOf
|
gptkb:TRK_family
receptor tyrosine kinase family
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:congenital_insensitivity_to_pain_with_anhidrosis
|
|
gptkbp:OMIM
|
191315
|
|
gptkbp:orthologInMouse
|
gptkb:Ntrk1
|
|
gptkbp:phosphorylates
|
tyrosine residues
|
|
gptkbp:product
|
gptkb:receptor_tyrosine_kinase
|
|
gptkbp:target
|
gptkb:entrectinib
gptkb:larotrectinib
|
|
gptkbp:UniProtID
|
gptkb:P04629
|
|
gptkbp:bfsParent
|
gptkb:entrectinib
gptkb:Entrectinib
|
|
gptkbp:bfsLayer
|
7
|