TGF-beta type III receptor

URI: https://gptkb.org/entity/TGF-beta_type_III_receptor
GPTKB entity
Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:receptor_tyrosine_kinase
gptkb:protein
gptkbp:alternativeName betaglycan
gptkbp:cytoplasmicDomain short
gptkbp:encodedBy TGFBR3 gene
gptkbp:Entrez_Gene_ID 7049
gptkbp:expressedIn many tissues
gptkbp:extracellularDomain present
gptkbp:function binds TGF-beta ligands
co-receptor for TGF-beta signaling
gptkbp:GO_term gptkb:GO:0005160
https://www.w3.org/2000/01/rdf-schema#label TGF-beta type III receptor
gptkbp:interactsWith gptkb:TGF-beta_type_II_receptor
gptkb:TGF-beta_type_I_receptor
gptkbp:locatedIn gptkb:cell_membrane
gptkbp:locatedOnChromosome 1p32-p33
gptkbp:molecularWeight ~110 kDa
gptkbp:mutationAssociatedWith gptkb:cancer
congenital heart defects
gptkbp:OMIM 600069
gptkbp:organism gptkb:Homo_sapiens
gptkbp:PDB 2PJY
gptkbp:postTranslationalModification glycosylation
gptkbp:role cell differentiation
embryonic development
cell growth regulation
tumor suppression
gptkbp:transmembraneDomains present
gptkbp:UniProtID Q03167
gptkbp:bfsParent gptkb:TGF-beta_receptor_family
gptkbp:bfsLayer 7