T-cell large granular lymphocyte leukemia

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:leukemia gptkb:lymphoproliferative_disorder gptkb:disease
gptkbp:affects	gptkb:T-cells blood
gptkbp:causedBy	clonal proliferation of cytotoxic T-cells
gptkbp:hasCellMarker	CD16+ CD57+ CD8+
gptkbp:hasDiagnosticMethod	peripheral blood smear flow cytometry T-cell receptor gene rearrangement
gptkbp:hasSexRatio	slight male predominance
gptkbp:ICD-10_code	gptkb:C91.8
gptkbp:medianAge	60 years
gptkbp:originatedIn	CD3+ T-cells
gptkbp:prevalence	rare
gptkbp:prognosis	gptkb:chronic_disease indolent course
gptkbp:riskFactor	gptkb:autoimmune_disease rheumatoid arthritis
gptkbp:subclassOf	gptkb:large_granular_lymphocyte_leukemia
gptkbp:symptom	gptkb:anemia fatigue splenomegaly neutropenia recurrent infections
gptkbp:synonym	gptkb:T-LGL_leukemia
gptkbp:treatment	gptkb:cyclophosphamide gptkb:cyclosporine gptkb:prednisone gptkb:methotrexate immunosuppressive therapy
gptkbp:bfsParent	gptkb:Large_Granular_Lymphocyte_Leukemia gptkb:T-cell_LGL_Leukemia
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	T-cell large granular lymphocyte leukemia