|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:associatedWith
|
gptkb:medulloblastoma
gptkb:holoprosencephaly
basal cell carcinoma
|
|
gptkbp:discoveredBy
|
gptkb:Cliff_Tabin
gptkb:Andrew_P._McMahon
gptkb:Philip_Ingham
|
|
gptkbp:encodedBy
|
SHH gene
|
|
gptkbp:Entrez_Gene_ID
|
6469
ENSG00000164690
|
|
gptkbp:expressedIn
|
notochord
floor plate
zone of polarizing activity
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:function
|
embryonic development
cell signaling
pattern formation
|
|
gptkbp:HGNC_ID
|
10848
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Sonic hedgehog
|
|
gptkbp:locatedOnChromosome
|
7q36
|
|
gptkbp:memberOf
|
hedgehog signaling pathway
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
birth defects
developmental disorders
|
|
gptkbp:namedAfter
|
gptkb:Sonic_the_Hedgehog
|
|
gptkbp:OMIM
|
600725
|
|
gptkbp:orthologIn
|
gptkb:Indian_hedgehog
gptkb:Desert_hedgehog
Drosophila hedgehog
|
|
gptkbp:postTranslationalModification
|
palmitoylation
cholesterol addition
|
|
gptkbp:recipient
|
gptkb:BOC
gptkb:CDON
gptkb:PTCH1
gptkb:PTCH2
GAS1
|
|
gptkbp:role
|
eye development
craniofacial development
lung development
hair follicle development
limb development
neural tube patterning
tooth development
gut development
|
|
gptkbp:symbol
|
gptkb:SHH
|
|
gptkbp:UniProtID
|
gptkb:Q15465
|
|
gptkbp:bfsParent
|
gptkb:Hedgehog_signaling_pathway
|
|
gptkbp:bfsLayer
|
7
|