Sestrin2

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:SESN2
Hi95
gptkbp:associatedWith gptkb:cancer
aging
neurodegenerative diseases
metabolic diseases
gptkbp:encodedBy gptkb:SESN2_gene
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function protection against oxidative stress
antioxidant response
regulation of cellular metabolism
inhibition of mTORC1 signaling
https://www.w3.org/2000/01/rdf-schema#label Sestrin2
gptkbp:inhibitedBy reactive oxygen species accumulation
gptkbp:length 480 amino acids
gptkbp:locatedOnChromosome 1p35.3
gptkbp:molecularWeight 57 kDa
gptkbp:regulates gptkb:AMPK_pathway
autophagy
cellular homeostasis
gptkbp:relatedTo gptkb:Sestrin3
Sestrin1
gptkbp:UniProtID gptkb:Q9Y6P5
gptkbp:upregulatedBy gptkb:p53
oxidative stress
gptkbp:bfsParent gptkb:SESN2
gptkbp:bfsLayer 7