Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
gptkb:Sestrin-2
PA26 Hi95 SES2 |
| gptkbp:associatedWith |
cellular senescence
metabolic homeostasis |
| gptkbp:encodes |
Sestrin-2 protein
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000168137
83667 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:function |
antioxidant activity
regulation of mTOR signaling pathway regulation of cellular response to oxidative stress |
| gptkbp:HGNC_ID |
HGNC:24658
|
| https://www.w3.org/2000/01/rdf-schema#label |
SESN2 gene
|
| gptkbp:inducedBy |
gptkb:p53
|
| gptkbp:involvedIn |
cell survival
autophagy AMPK activation inhibition of ROS accumulation suppression of tumorigenesis |
| gptkbp:locatedOnChromosome |
1p35.3
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
metabolic disorders |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Sestrin2
|
| gptkbp:UniProtID |
gptkb:Q9Y6P5
|
| gptkbp:upregulatedBy |
oxidative stress
DNA damage |
| gptkbp:bfsParent |
gptkb:SESN2
|
| gptkbp:bfsLayer |
7
|