Sestrin-2

GPTKB entity

Statements (25)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:SESN2
Hi95
gptkbp:associatedWith gptkb:cancer
neurodegenerative diseases
metabolic diseases
gptkbp:encodedBy gptkb:SESN2_gene
gptkbp:expressedIn various human tissues
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function antioxidant activity
regulation of mTOR signaling
regulation of oxidative stress
https://www.w3.org/2000/01/rdf-schema#label Sestrin-2
gptkbp:involvedIn aging
autophagy
cellular response to stress
gptkbp:length 480 amino acids
gptkbp:locatedOnChromosome 1p35.3
gptkbp:molecularWeight 57 kDa
gptkbp:regulates gptkb:AMPK_pathway
mTORC1 pathway
gptkbp:UniProtID gptkb:Q9Y6P5
gptkbp:upregulatedBy gptkb:p53
gptkbp:bfsParent gptkb:SESN2
gptkbp:bfsLayer 7