|
gptkbp:instanceOf
|
neurotransmitter
|
|
gptkbp:aroma
|
odorless
|
|
gptkbp:associatedWith
|
gptkb:depression
anxiety
migraine
irritable bowel syndrome
|
|
gptkbp:biosynthesized_from
|
tryptophan hydroxylase
|
|
gptkbp:CASNumber
|
50-67-9
|
|
gptkbp:category
|
biogenic amine
indoleamine
monoamine neurotransmitter
|
|
gptkbp:chemicalFormula
|
C10H12N2O
|
|
gptkbp:color
|
white to yellowish powder
|
|
gptkbp:degradedBy
|
gptkb:monoamine_oxidase
|
|
gptkbp:discoveredBy
|
gptkb:Maurice_M._Rapport
|
|
gptkbp:discoveredIn
|
1948
|
|
gptkbp:foundIn
|
gastrointestinal tract
central nervous system
blood platelets
|
|
gptkbp:function
|
regulation of mood
regulation of appetite
regulation of memory
regulation of learning
regulation of intestinal movements
regulation of sleep
regulation of vasoconstriction
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Serotonin
|
|
gptkbp:IUPACName
|
5-hydroxytryptamine
|
|
gptkbp:meltingPoint
|
167°C
|
|
gptkbp:MeSH_ID
|
D012701
|
|
gptkbp:metabolism
|
gptkb:5-HIAA
|
|
gptkbp:molecularWeight
|
176.215 g/mol
|
|
gptkbp:pKa
|
10.02
|
|
gptkbp:predecessor
|
tryptophan
|
|
gptkbp:producedBy
|
neurons
enterochromaffin cells
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL39
28790
5202
|
|
gptkbp:receptors
|
5-HT receptors
|
|
gptkbp:releaseMechanism
|
exocytosis
|
|
gptkbp:reuptakeBy
|
gptkb:serotonin_transporter_(SERT)
|
|
gptkbp:solubility
|
soluble
|
|
gptkbp:storage
|
synaptic vesicles
|
|
gptkbp:synonym
|
gptkb:5-HT
5-hydroxytryptamine
|
|
gptkbp:targetOfDrug
|
gptkb:tricyclic_antidepressants
gptkb:SSRIs
MAOIs
|
|
gptkbp:UNII
|
333DO1RDJY
|
|
gptkbp:bfsParent
|
gptkb:Chemical_synapse
gptkb:neurotransmitter
gptkb:Platelet
|
|
gptkbp:bfsLayer
|
5
|