|
gptkbp:instanceOf
|
gptkb:chemical_compound
|
|
gptkbp:approvalYear
|
1899
|
|
gptkbp:ATCCode
|
gptkb:N02BA01
B01AC06
|
|
gptkbp:bioavailability
|
80-100%
|
|
gptkbp:CASNumber
|
50-78-2
|
|
gptkbp:contraindication
|
gptkb:peptic_ulcer
gptkb:bleeding_disorder
asthma
children with viral infections
|
|
gptkbp:drugClass
|
gptkb:nonsteroidal_anti-inflammatory_drug
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:halfLife
|
2-3 hours
|
|
gptkbp:hasInChIKey
|
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
|
|
gptkbp:hasLogP
|
1.19
|
|
gptkbp:hasMolecularFormula
|
C9H8O4
|
|
gptkbp:hasPharmacologyAction
|
gptkb:analgesic
gptkb:antipyretic
anti-inflammatory
antiplatelet
|
|
gptkbp:haspKa
|
3.5
|
|
gptkbp:hasSMILES
|
CC(=O)Oc1ccccc1C(=O)O
|
|
gptkbp:hasUNII
|
R16CO5Y76E
|
|
gptkbp:hasWikipediaPage
|
gptkb:Aspirin
|
|
gptkbp:indication
|
fever
pain
inflammation
prevention of cardiovascular events
|
|
gptkbp:isApprovedDrug
|
true
|
|
gptkbp:manufacturer
|
gptkb:Bayer
|
|
gptkbp:meltingPoint
|
135°C
|
|
gptkbp:MeSH_ID
|
D001241
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
180.16
|
|
gptkbp:name
|
gptkb:Aspirin
|
|
gptkbp:originatedIn
|
synthesized
|
|
gptkbp:PubChem_CID
|
2244
DB00945
15365
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
rectal
|
|
gptkbp:sideEffect
|
gastrointestinal bleeding
allergic reaction
ulcer
|
|
gptkbp:synonym
|
gptkb:2-Acetoxybenzoic_acid
gptkb:ASA
gptkb:Acetylsalicylic_acid
|
|
gptkbp:target
|
gptkb:PTGS2
gptkb:PTGS1
|
|
gptkbp:bfsParent
|
gptkb:Adrenaline
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CHEMBL39
|