|
gptkbp:instanceOf
|
gptkb:chemical_compound
neurotransmitter
|
|
gptkbp:agonistsUsedFor
|
antidepressants
|
|
gptkbp:alsoKnownAs
|
serotonin
|
|
gptkbp:antagonistsUsedFor
|
antiemetics
antimigraine drugs
|
|
gptkbp:biosynthesized_from
|
tryptophan
|
|
gptkbp:CASNumber
|
50-67-9
|
|
gptkbp:category
|
biogenic amine
indoleamine
monoamine neurotransmitter
|
|
gptkbp:chemicalFormula
|
C10H12N2O
|
|
gptkbp:degradedBy
|
gptkb:monoamine_oxidase
|
|
gptkbp:discoveredBy
|
gptkb:Maurice_M._Rapport
|
|
gptkbp:discoveredIn
|
1948
|
|
gptkbp:foundIn
|
gastrointestinal tract
central nervous system
blood platelets
|
|
gptkbp:fullName
|
5-hydroxytryptamine
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
5-HT
|
|
gptkbp:IUPACName
|
5-hydroxytryptamine
|
|
gptkbp:molecularWeight
|
176.215 g/mol
|
|
gptkbp:predecessor
|
tryptophan
|
|
gptkbp:receptors
|
5-HT1
5-HT2
5-HT3
5-HT4
5-HT5
5-HT6
5-HT7
|
|
gptkbp:regulates
|
memory
learning
sleep
appetite
mood
|
|
gptkbp:releaseYear
|
neurons
|
|
gptkbp:reuptakeBy
|
gptkb:serotonin_transporter_(SERT)
|
|
gptkbp:role
|
gptkb:depression
anxiety
migraine
blood clotting
gastrointestinal motility
vasoconstriction
|
|
gptkbp:storage
|
synaptic vesicles
|
|
gptkbp:target
|
gptkb:tricyclic_antidepressants
gptkb:SSRIs
MAOIs
|
|
gptkbp:bfsParent
|
gptkb:Serotonin
|
|
gptkbp:bfsLayer
|
6
|