Secreted Frizzled-Related Proteins
GPTKB entity
Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
sFRPs
|
| gptkbp:binds |
gptkb:Frizzled_receptors
gptkb:Wnt_proteins |
| gptkbp:domain |
Frizzled-like cysteine-rich domain
|
| gptkbp:function |
Wnt signaling pathway modulation
antagonist of Wnt proteins |
| https://www.w3.org/2000/01/rdf-schema#label |
Secreted Frizzled-Related Proteins
|
| gptkbp:location |
extracellular space
|
| gptkbp:member |
gptkb:sFRP1
gptkb:sFRP2 gptkb:sFRP3 gptkb:sFRP4 gptkb:sFRP5 |
| gptkbp:proteinFamily |
FRZB family
|
| gptkbp:regulates |
apoptosis
cell differentiation cell proliferation embryonic development |
| gptkbp:role |
gptkb:cancer
gptkb:cardiovascular_disease bone disorders fibrosis |
| gptkbp:bfsParent |
gptkb:sFRP_proteins
|
| gptkbp:bfsLayer |
7
|