Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:FRP
FRZB1 Frizzled-related protein |
| gptkbp:associatedWith |
osteoarthritis
|
| gptkbp:binds |
gptkb:Wnt_proteins
frizzled receptors |
| gptkbp:encodedBy |
FRZB gene
|
| gptkbp:expressedIn |
gptkb:bone
brain collagen |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:fullName |
Secreted frizzled-related protein 3
|
| gptkbp:function |
modulates Wnt signaling pathway
|
| gptkbp:gene |
FRZB
|
| https://www.w3.org/2000/01/rdf-schema#label |
sFRP3
|
| gptkbp:inhibitedBy |
gptkb:Wnt_signaling
|
| gptkbp:locatedOnChromosome |
2q32.1
|
| gptkbp:location |
extracellular space
|
| gptkbp:molecularWeight |
~36 kDa
|
| gptkbp:mutationAssociatedWith |
hip dysplasia
femoral head osteonecrosis |
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:role |
skeletal development
cartilage formation |
| gptkbp:structure |
contains cysteine-rich domain
|
| gptkbp:UniProtID |
Q92765
|
| gptkbp:bfsParent |
gptkb:sFRP_proteins
|
| gptkbp:bfsLayer |
7
|