|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Manganese_superoxide_dismutase
gptkb:MnSOD
|
|
gptkbp:associatedWith
|
gptkb:Amyotrophic_lateral_sclerosis
gptkb:cancer
cardiomyopathy
Deafness, autosomal recessive 6
|
|
gptkbp:cofactor
|
Manganese
|
|
gptkbp:EC_number
|
1.15.1.1
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000112096
6648
|
|
gptkbp:fullName
|
Superoxide dismutase [Mn], mitochondrial
|
|
gptkbp:function
|
Destroys superoxide anion radicals
|
|
gptkbp:gene
|
gptkb:SOD2
|
|
gptkbp:GO_term
|
aging
apoptotic process
neuroprotection
mitochondrion
response to oxidative stress
superoxide dismutase activity
metal ion binding
cellular response to hydrogen peroxide
|
|
gptkbp:hasIsoform
|
Isoform 1
Isoform 2
|
|
gptkbp:HGNC_ID
|
11179
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SODM HUMAN
|
|
gptkbp:length
|
222 amino acids
|
|
gptkbp:locatedOnChromosome
|
6q25.3
|
|
gptkbp:location
|
mitochondrion
|
|
gptkbp:molecularWeight
|
24,713 Da
|
|
gptkbp:OMIM
|
147460
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
9606
|
|
gptkbp:pathway
|
Cellular response to oxidative stress
Reactive oxygen species detoxification
|
|
gptkbp:PDB
|
gptkb:1QNK
gptkb:1LUV
gptkb:1N0J
1VEW
|
|
gptkbp:postTranslationalModification
|
Methylation
Phosphorylation
Acetylation
|
|
gptkbp:reviewedBy
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:sequenceStatus
|
Reviewed
|
|
gptkbp:subcellularLocation
|
Mitochondrial matrix
|
|
gptkbp:tissue_specificity
|
Expressed in most tissues
|
|
gptkbp:UniProtID
|
P04179
|
|
gptkbp:bfsParent
|
gptkb:SOD2
|
|
gptkbp:bfsLayer
|
7
|