|
gptkbp:instanceOf
|
gptkb:protein
small molecule
|
|
gptkbp:activatedBy
|
guanine nucleotide exchange factors
|
|
gptkbp:binds
|
gptkb:GDP
gptkb:GTP
|
|
gptkbp:discoveredBy
|
1985
|
|
gptkbp:encodedBy
|
RHO gene family
|
|
gptkbp:foundIn
|
eukaryotes
|
|
gptkbp:hasMember
|
gptkb:RhoA
gptkb:Rac1
gptkb:Cdc42
gptkb:Rac2
gptkb:Rac3
gptkb:RhoB
gptkb:RhoC
gptkb:RhoD
gptkb:RhoF
gptkb:RhoG
gptkb:RhoH
gptkb:RhoU
gptkb:RhoV
gptkb:Rnd1
gptkb:Rnd2
gptkb:Rnd3
RhoBTB1
RhoBTB2
RhoBTB3
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Rho GTPases
|
|
gptkbp:inhibitedBy
|
GTPase-activating proteins
|
|
gptkbp:involves
|
wound healing
angiogenesis
cancer progression
immune response
neurodevelopment
cellular transformation
|
|
gptkbp:regulates
|
gene expression
vesicle trafficking
cell cycle progression
cell migration
cell polarity
actin cytoskeleton
cell adhesion
cell morphogenesis
guanine nucleotide dissociation inhibitors
|
|
gptkbp:studiedBy
|
cancer research
cell biology
neuroscience
|
|
gptkbp:subclassOf
|
gptkb:Ras_superfamily
|
|
gptkbp:target
|
therapeutic drugs
bacterial toxins
|
|
gptkbp:bfsParent
|
gptkb:RhoGAP
gptkb:exocyst_complex
gptkb:Dbl_family_proteins
gptkb:Ras_superfamily_GEFs
gptkb:Switch_II_region
|
|
gptkbp:bfsLayer
|
7
|