Retinoic acid-inducible gene I
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:activatedBy |
interferon production
|
| gptkbp:alsoKnownAs |
gptkb:RIG-I
|
| gptkbp:associatedWith |
autoimmune diseases
|
| gptkbp:binds |
double-stranded RNA
5'-triphosphate RNA |
| gptkbp:discoveredIn |
2004
|
| gptkbp:domain |
gptkb:CARD_domain
helicase domain |
| gptkbp:encodedBy |
gptkb:DDX58_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
innate immune response
viral RNA sensor |
| https://www.w3.org/2000/01/rdf-schema#label |
Retinoic acid-inducible gene I
|
| gptkbp:inhibitedBy |
viral proteins
|
| gptkbp:interactsWith |
gptkb:MAVS
|
| gptkbp:involvedIn |
type I interferon signaling pathway
pattern recognition receptor pathway |
| gptkbp:locatedIn |
gptkb:cytoplasm
|
| gptkbp:locatedOnChromosome |
gptkb:2q24.2
|
| gptkbp:orthologIn |
gptkb:Danio_rerio
gptkb:Mus_musculus |
| gptkbp:regulates |
antiviral response
|
| gptkbp:structure |
ATP-dependent RNA helicase
|
| gptkbp:UniProtID |
gptkb:O95786
|
| gptkbp:bfsParent |
gptkb:RIG-I_signaling_pathway
gptkb:RIG-I |
| gptkbp:bfsLayer |
8
|