Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:NF-κB_pathway
interferon response |
| gptkbp:alternativeName |
gptkb:DDX58
gptkb:Retinoic_acid-inducible_gene_I |
| gptkbp:discoveredIn |
2004
|
| gptkbp:domain |
gptkb:CARD_domain
helicase C-terminal domain DEAD box helicase domain |
| gptkbp:encodedBy |
gptkb:DDX58_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
innate immune receptor
viral RNA sensor |
| https://www.w3.org/2000/01/rdf-schema#label |
RIG-I
|
| gptkbp:interactsWith |
gptkb:MAVS
gptkb:TRIM25 viral RNA |
| gptkbp:involvedIn |
antiviral defense
pattern recognition receptor signaling |
| gptkbp:locatedIn |
gptkb:cytoplasm
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_9q33.1
|
| gptkbp:mutationAssociatedWith |
gptkb:Singleton-Merten_syndrome
|
| gptkbp:recognizedBy |
double-stranded RNA
5'-triphosphate RNA |
| gptkbp:regulates |
type I interferon production
|
| gptkbp:species |
gptkb:human
gptkb:mouse other mammals |
| gptkbp:UniProtID |
gptkb:O95786
|
| gptkbp:bfsParent |
gptkb:LGP2
|
| gptkbp:bfsLayer |
7
|