RIG-I signaling pathway

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf biological pathway
gptkbp:activatedBy type I interferon production
gptkbp:cause expression of interferon-stimulated genes
gptkbp:detects viral RNA
https://www.w3.org/2000/01/rdf-schema#label RIG-I signaling pathway
gptkbp:involves gptkb:TBK1
gptkb:NF-κB
gptkb:IRF3
TRAF3
MAVS protein
RIG-I protein
gptkbp:is_discovered_in mammals
gptkbp:is_negatively_regulated_by gptkb:LGP2
viral proteins
gptkbp:launched innate immune response
gptkbp:namedAfter gptkb:Retinoic_acid-inducible_gene_I
gptkbp:occurredIn gptkb:cytoplasm
gptkbp:partOf antiviral defense
gptkbp:regulates phosphorylation
ubiquitination
gptkbp:requires host defense against RNA viruses
gptkbp:bfsParent gptkb:OASL_protein
gptkbp:bfsLayer 7