|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activatedBy
|
gptkb:NF-kappaB_pathway
IRF3 pathway
|
|
gptkbp:alternativeName
|
gptkb:VISA
CARD adaptor inducing IFN-beta
Cardif
IPS-1
|
|
gptkbp:discoveredIn
|
2005
|
|
gptkbp:domain
|
gptkb:CARD_domain
transmembrane domain
|
|
gptkbp:encodedBy
|
MAVS gene
|
|
gptkbp:fullName
|
Mitochondrial Antiviral-Signaling Protein
|
|
gptkbp:function
|
innate immune response
antiviral signaling
|
|
gptkbp:gene
|
gptkb:MAVS
|
|
gptkbp:GO_term
|
GO:0005739 (mitochondrion)
GO:0002221 (pattern recognition receptor signaling pathway)
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAVS
|
|
gptkbp:inhibitedBy
|
viral proteases
|
|
gptkbp:interactsWith
|
gptkb:MDA5
gptkb:RIG-I
|
|
gptkbp:locatedIn
|
mitochondrial outer membrane
|
|
gptkbp:locatedOnChromosome
|
human chromosome 20p13
|
|
gptkbp:mutationAssociatedWith
|
autoimmune diseases
viral susceptibility
|
|
gptkbp:orthologIn
|
gptkb:Danio_rerio
gptkb:Mus_musculus
|
|
gptkbp:phosphorylates
|
Serine 442
|
|
gptkbp:regulates
|
apoptosis
type I interferon production
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:UniProtID
|
Q7Z434
|
|
gptkbp:bfsParent
|
gptkb:MDA5
gptkb:RIG-I
gptkb:RIG-I-like_receptor_signaling_pathway
gptkb:Mavs_Gaming
gptkb:CARD_domain
|
|
gptkbp:bfsLayer
|
8
|