Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
tumor suppressor
|
| gptkbp:activatedBy |
growth factors
|
| gptkbp:associatedWith |
gptkb:cancer
colorectal cancer melanoma pancreatic cancer |
| gptkbp:decommissioned |
GTP hydrolysis
|
| gptkbp:discoveredBy |
gptkb:Robert_Weinberg
|
| gptkbp:encodes |
gptkb:Ras_protein
|
| gptkbp:firstDescribed |
1982
|
| gptkbp:foundIn |
animals
humans |
| gptkbp:function |
GTPase activity
|
| gptkbp:hasIsoform |
gptkb:HRAS
gptkb:KRAS gptkb:NRAS |
| https://www.w3.org/2000/01/rdf-schema#label |
Ras oncogene
|
| gptkbp:involvedIn |
cell signaling
cell growth regulation |
| gptkbp:locatedOn |
gptkb:chromosome_11_(HRAS)
gptkb:chromosome_12_(KRAS) gptkb:chromosome_1_(NRAS) |
| gptkbp:memberOf |
gptkb:Ras_gene_family
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
|
| gptkbp:regulates |
gptkb:MAPK_pathway
gptkb:PI3K_pathway |
| gptkbp:target |
anticancer drugs
|
| gptkbp:bfsParent |
gptkb:Der,_Channing_J.
|
| gptkbp:bfsLayer |
7
|