|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activatedBy
|
guanine nucleotide exchange factors (GEFs)
|
|
gptkbp:associatedWith
|
membrane compartments
|
|
gptkbp:contains
|
gptkb:Rab5
gptkb:Rab4
gptkb:Rab7
gptkb:Rab1
gptkb:Rab10
gptkb:Rab11
gptkb:Rab2
gptkb:Rab27
gptkb:Rab3
gptkb:Rab35
gptkb:Rab6
gptkb:Rab8
gptkb:Rab9
|
|
gptkbp:decommissioned
|
GTPase-activating proteins (GAPs)
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:foundIn
|
eukaryotes
|
|
gptkbp:function
|
membrane trafficking
regulation of vesicle trafficking
|
|
gptkbp:GO_term
|
GO:0005525
GO:0003924
|
|
gptkbp:hasGTPaseActivity
|
true
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Rab family GTPase
|
|
gptkbp:interactsWith
|
gptkb:Rab_effector_proteins
GDP dissociation inhibitors (GDI)
Rab escort proteins (REP)
|
|
gptkbp:locale
|
membranes
cytosol
|
|
gptkbp:memberOf
|
gptkb:Ras_superfamily
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:Griscelli_syndrome
diseases such as Charcot-Marie-Tooth disease
|
|
gptkbp:namedAfter
|
gptkb:Ras-related_in_brain
|
|
gptkbp:numberOfMembersInHumanGenome
|
over 60
|
|
gptkbp:orthologIn
|
gptkb:yeast
animals
plants
|
|
gptkbp:postTranslationalModification
|
prenylation
|
|
gptkbp:regulates
|
autophagy
endocytosis
exocytosis
vesicle docking
vesicle fusion
organelle identity
|
|
gptkbp:subclassOf
|
small molecule
|
|
gptkbp:bfsParent
|
gptkb:Ypt51_(yeast)
|
|
gptkbp:bfsLayer
|
7
|