|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:cellularComponent
|
gptkb:cell_membrane
gptkb:cytoplasm
|
|
gptkbp:encodedBy
|
gptkb:RAB7A_gene
|
|
gptkbp:Entrez_Gene_ID
|
7879
|
|
gptkbp:function
|
autophagosome-lysosome fusion
late endosome maturation
lysosome biogenesis
regulation of endo-lysosomal trafficking
|
|
gptkbp:GO
|
GO:0005764 (lysosome)
GO:0005770 (late endosome)
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Rab7
|
|
gptkbp:interactsWith
|
gptkb:FYCO1
gptkb:RILP
gptkb:Vps39
gptkb:Vps41
|
|
gptkbp:locale
|
lysosome membrane
late endosome membrane
|
|
gptkbp:locatedOnChromosome
|
3q21.3
|
|
gptkbp:memberOf
|
gptkb:Rab_family
gptkb:Ras_superfamily
|
|
gptkbp:molecularWeight
|
23 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Charcot-Marie-Tooth_disease_type_2B
gptkb:hereditary_sensory_neuropathy_type_1C
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:RAB7A_(human)
gptkb:Rab7_(mouse)
gptkb:Ypt7_(yeast)
|
|
gptkbp:postTranslationalModification
|
prenylation
|
|
gptkbp:regulates
|
autophagy
phagosome maturation
endosome-lysosome fusion
receptor degradation
|
|
gptkbp:UniProtID
|
gptkb:P51149
|
|
gptkbp:bfsParent
|
gptkb:Rab_family
gptkb:Rab5
gptkb:Rab_protein
|
|
gptkbp:bfsLayer
|
6
|