Statements (52)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
gptkbp:associatedWith |
gptkb:cancer
neurodegenerative diseases |
gptkbp:encodedBy |
RAB11A gene
RAB11B gene RAB25 gene |
gptkbp:form |
GTP-bound
|
gptkbp:foundIn |
gptkb:trans-Golgi_network
gptkb:cytoplasm endosomes |
gptkbp:function |
regulation of vesicle trafficking
endocytic recycling |
gptkbp:GTPase_activity |
yes
|
gptkbp:hasIsoform |
Rab11A
Rab11B Rab25 |
https://www.w3.org/2000/01/rdf-schema#label |
Rab11
|
gptkbp:inactive_form |
GDP-bound
|
gptkbp:interactsWith |
EHD proteins
Rab11-FIP proteins myosin Vb |
gptkbp:locale |
pericentriolar recycling endosomes
|
gptkbp:member |
gptkb:Rab_family
gptkb:Ras_superfamily |
gptkbp:ortholog_in_Drosophila |
gptkb:Rab11
|
gptkbp:orthologIn |
RAB11A
|
gptkbp:orthologInMouse |
Rab11a
|
gptkbp:postTranslationalModification |
prenylation
phosphorylation |
gptkbp:regulates |
cell polarity
cytokinesis exocytosis transferrin receptor recycling recycling of GLUT4 recycling of integrins E-cadherin trafficking apical membrane delivery membrane recycling plasma membrane protein recycling recycling endosome pathway recycling of AMPA receptors recycling of EGFR recycling of GLUT1 recycling of LDL receptor recycling of MHC class I molecules recycling of TCR recycling of aquaporin-2 recycling of beta-adrenergic receptors |
gptkbp:bfsParent |
gptkb:Rab_family
gptkb:Rab_protein |
gptkbp:bfsLayer |
6
|