|
gptkbp:instanceOf
|
gptkb:protein
small molecule
|
|
gptkbp:activatedBy
|
guanine nucleotide exchange factors (GEFs)
|
|
gptkbp:associatedWith
|
gptkb:Golgi_apparatus
gptkb:plasma_membrane
endosomes
lysosomes
|
|
gptkbp:binds
|
gptkb:GDP
gptkb:GTP
|
|
gptkbp:decommissioned
|
GTPase-activating proteins (GAPs)
|
|
gptkbp:discoveredBy
|
Pereira-Leal JB
Seabra MC
|
|
gptkbp:example
|
gptkb:Rab5
gptkb:Rab7
gptkb:Rab1
gptkb:Rab11
|
|
gptkbp:foundIn
|
eukaryotic cells
|
|
gptkbp:function
|
regulation of vesicle trafficking
|
|
gptkbp:GO_term
|
GO:0005525
GO:0003924
GO:0006886
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Rab GTPases
|
|
gptkbp:interactsWith
|
GDP dissociation inhibitor (GDI)
Rab escort protein (REP)
|
|
gptkbp:locale
|
membranes
cytosol
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Charcot-Marie-Tooth_disease
gptkb:Griscelli_syndrome
X-linked mental retardation
|
|
gptkbp:numberOfMembers
|
over 60 in humans
|
|
gptkbp:postTranslationalModification
|
prenylation
|
|
gptkbp:regulates
|
phagocytosis
autophagy
endocytosis
exocytosis
membrane trafficking
vesicle fusion
membrane fusion
cargo selection
vesicle formation
vesicle movement
protein sorting
membrane docking
membrane tethering
organelle identity
receptor recycling
vesicle motility
vesicle uncoating
|
|
gptkbp:subclassOf
|
gptkb:Ras_superfamily
|
|
gptkbp:bfsParent
|
gptkb:LRRK2
gptkb:exocyst_complex
gptkb:Ras_superfamily_GEFs
gptkb:GDIs_(GDP_dissociation_inhibitors)
gptkb:Switch_II_region
gptkb:Rab_effector_proteins
|
|
gptkbp:bfsLayer
|
7
|