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gptkbp:instanceOf
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gptkb:protein
|
|
gptkbp:associatedWith
|
gptkb:cancer
neurological disorders
human diseases
|
|
gptkbp:biologicalProcess
|
GTP binding
GTPase activity
endocytosis
exocytosis
membrane trafficking
|
|
gptkbp:database
|
gptkb:NCBI_Gene
gptkb:Gene_Ontology
gptkb:UniProt
|
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gptkbp:discoveredBy
|
Takai Yuji
|
|
gptkbp:firstDescribed
|
1980s
|
|
gptkbp:foundIn
|
eukaryotes
|
|
gptkbp:function
|
regulation of vesicle trafficking
|
|
gptkbp:GO_term
|
GO:0005525
GO:0003924
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Rab GTPase family
|
|
gptkbp:locale
|
membranes
cytosol
|
|
gptkbp:member
|
gptkb:Rab5
gptkb:Rab4
gptkb:Rab7
gptkb:Rab1
gptkb:Rab10
gptkb:Rab11
gptkb:Rab2
gptkb:Rab27
gptkb:Rab3
gptkb:Rab35
gptkb:Rab6
gptkb:Rab8
gptkb:Rab9
|
|
gptkbp:numberOfMembers
|
over 60 in humans
|
|
gptkbp:postTranslationalModification
|
prenylation
|
|
gptkbp:regulates
|
gptkb:GDP_dissociation_inhibitors_(GDIs)
GTPase-activating proteins (GAPs)
vesicle fusion
vesicle formation
vesicle movement
GDP/GTP exchange factors (GEFs)
|
|
gptkbp:relatedTo
|
gptkb:Rho_GTPase_family
gptkb:SNARE_proteins
Arf GTPase family
Ran GTPase family
|
|
gptkbp:subclassOf
|
gptkb:Ras_superfamily
small molecule
|
|
gptkbp:UniProtID
|
gptkb:Rab_family
|
|
gptkbp:bfsParent
|
gptkb:EFC27
|
|
gptkbp:bfsLayer
|
8
|