|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:associatedWith
|
tetanus
botulism
|
|
gptkbp:component
|
vesicle trafficking system
|
|
gptkbp:database
|
gptkb:Gene_Ontology:_GO:0005484
gptkb:UniProt:Q9H0R8
|
|
gptkbp:discoveredBy
|
gptkb:James_Rothman
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:example
|
gptkb:SNAP-25
gptkb:syntaxin
gptkb:VAMP
|
|
gptkbp:foundIn
|
eukaryotic cells
|
|
gptkbp:fullName
|
gptkb:Soluble_NSF_Attachment_Protein_Receptor_proteins
|
|
gptkbp:function
|
mediate membrane fusion
mediate vesicle fusion
|
|
gptkbp:GO_term
|
GO:0005484
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SNARE proteins
|
|
gptkbp:interactsWith
|
gptkb:NSF_protein
gptkb:SNAP_proteins
|
|
gptkbp:locale
|
gptkb:endoplasmic_reticulum
gptkb:Golgi_apparatus
gptkb:plasma_membrane
endosomes
lysosomes
synaptic vesicles
|
|
gptkbp:mechanismOfAction
|
form SNARE complex
zippering of SNARE motifs
|
|
gptkbp:orthologIn
|
gptkb:yeast
animals
plants
|
|
gptkbp:regulates
|
gptkb:synaptotagmin
gptkb:Munc18
gptkb:complexin
|
|
gptkbp:requires
|
synaptic transmission
membrane trafficking
hormone secretion
|
|
gptkbp:reviewedBy
|
gptkb:Nature_Reviews_Molecular_Cell_Biology
gptkb:Annual_Review_of_Cell_and_Developmental_Biology
Cell
|
|
gptkbp:role
|
neurotransmitter release
endocytosis
exocytosis
intracellular trafficking
|
|
gptkbp:structure
|
coiled-coil domain
|
|
gptkbp:subclassOf
|
membrane proteins
|
|
gptkbp:target
|
gptkb:tetanus_toxin
botulinum toxin
|
|
gptkbp:type
|
gptkb:t-SNARE
gptkb:v-SNARE
|
|
gptkbp:bfsParent
|
gptkb:SNARE_hypothesis
|
|
gptkbp:bfsLayer
|
6
|