Statements (40)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
Ras-related protein Rab-7a
|
| gptkbp:associatedWith |
Charcot-Marie-Tooth disease type 2B (in human ortholog)
|
| gptkbp:biologicalProcess |
GTPase activity
|
| gptkbp:encodedBy |
Rab7 gene (mouse)
|
| gptkbp:Entrez_Gene_ID |
19349
|
| gptkbp:expressedIn |
ubiquitous
|
| gptkbp:function |
late endosome maturation
lysosome biogenesis regulation of endo-lysosomal trafficking |
| gptkbp:GO_term |
GO:0006914 (autophagy)
GO:0006886 (intracellular protein transport) GO:0005764 (lysosome) |
| https://www.w3.org/2000/01/rdf-schema#label |
Rab7 (mouse)
|
| gptkbp:interactsWith |
gptkb:FYCO1
gptkb:RILP gptkb:Vps39 HOPS complex ORP1L |
| gptkbp:length |
207 amino acids
|
| gptkbp:locatedOnChromosome |
gptkb:mouse_chromosome_9
|
| gptkbp:location |
lysosome membrane
late endosome membrane |
| gptkbp:molecularWeight |
23.6 kDa
|
| gptkbp:organism |
gptkb:Mus_musculus
|
| gptkbp:orthologIn |
Rab7 (human)
|
| gptkbp:pathway |
autophagy
endocytosis phagosome maturation |
| gptkbp:PDB |
1T91
1VG0 |
| gptkbp:postTranslationalModification |
prenylation
phosphorylation |
| gptkbp:sequenceStatus |
reviewed
|
| gptkbp:structure |
contains GTP-binding domain
|
| gptkbp:subfamily |
gptkb:Rab_family
|
| gptkbp:superfamily |
Ras superfamily of small GTPases
|
| gptkbp:UniProtID |
P51150
|
| gptkbp:bfsParent |
gptkb:Rab7
|
| gptkbp:bfsLayer |
7
|