|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:ARH12
gptkb:RHOH12
gptkb:ras_homolog_family_member_A
|
|
gptkbp:associatedWith
|
gptkb:cancer
cardiovascular diseases
|
|
gptkbp:discoveredIn
|
1985
|
|
gptkbp:encodes
|
gptkb:RhoA_protein
|
|
gptkbp:Entrez_Gene_ID
|
387
ENSG00000067560
|
|
gptkbp:function
|
signal transduction
regulation of actin cytoskeleton
|
|
gptkbp:HGNC_ID
|
HGNC:667
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RHOA gene
|
|
gptkbp:locatedOnChromosome
|
3p21.31
|
|
gptkbp:mutationAssociatedWith
|
gptkb:T-cell_lymphoma
gptkb:diffuse-type_gastric_cancer
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Rhoa
|
|
gptkbp:product
|
gptkb:GTP-binding_protein_RhoA
|
|
gptkbp:proteinFamily
|
gptkb:Rho_GTPase_family
|
|
gptkbp:regulates
|
gptkb:synaptic_plasticity
apoptosis
cell proliferation
wound healing
gene expression
angiogenesis
cell cycle progression
cell migration
glucose metabolism
inflammation
metastasis
blood pressure
cell shape
neurite outgrowth
cell polarity
cell adhesion
cell motility
cytokinesis
insulin signaling
fibrosis
immune cell trafficking
smooth muscle contraction
axon guidance
platelet aggregation
tumor progression
endothelial permeability
vascular tone
|
|
gptkbp:UniProtID
|
P61586
|
|
gptkbp:bfsParent
|
gptkb:RhoA
gptkb:Rho_protein
|
|
gptkbp:bfsLayer
|
6
|