Statements (29)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:associatedWith |
gptkb:cancer
|
gptkbp:discoveredIn |
1980s
|
gptkbp:encodes |
small GTPase proteins
|
gptkbp:foundIn |
humans
other animals |
gptkbp:function |
signal transduction
regulation of cell proliferation |
https://www.w3.org/2000/01/rdf-schema#label |
RAS oncogene family
|
gptkbp:includes |
gptkb:HRAS
gptkb:KRAS gptkb:NRAS |
gptkbp:involvedIn |
cell differentiation
apoptosis regulation |
gptkbp:locatedOnChromosome |
gptkb:chromosome_11_(HRAS)
gptkb:chromosome_12_(KRAS) gptkb:chromosome_1_(NRAS) |
gptkbp:mutationAssociatedWith |
missense mutation
point mutation oncogenic transformation |
gptkbp:namedAfter |
gptkb:rat_sarcoma_virus
|
gptkbp:orthologIn |
gptkb:Caenorhabditis_elegans
gptkb:Drosophila_melanogaster |
gptkbp:product |
gptkb:G_protein-coupled_receptor
|
gptkbp:relatedTo |
gptkb:MAPK_pathway
gptkb:PI3K_pathway |
gptkbp:bfsParent |
gptkb:190020_(HRAS)
gptkb:human_NRAS |
gptkbp:bfsLayer |
6
|