protein kinase, AMP-activated, alpha 1 catalytic subunit

URI: https://gptkb.org/entity/protein_kinase,_AMP-activated,_alpha_1_catalytic_subunit
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy gptkb:AMP
gptkb:ADP
phosphorylation
gptkbp:alternativeName gptkb:AMPK_alpha-1
gptkb:AMP-activated_protein_kinase_catalytic_subunit_alpha-1
gptkbp:associatedWith gptkb:type_2_diabetes
obesity
gptkbp:biologicalProcess kinase activity
gptkbp:component gptkb:AMP-activated_protein_kinase_complex
gptkbp:enzymeCommissionNumber gptkb:EC_2.7.11.31
gptkbp:expressedIn gptkb:skeletal_muscle
liver
adipose tissue
gptkbp:function catalytic subunit of AMPK
gptkbp:gene gptkb:PRKAA1
gptkbp:HGNC_ID 9381
https://www.w3.org/2000/01/rdf-schema#label protein kinase, AMP-activated, alpha 1 catalytic subunit
gptkbp:inhibitedBy gptkb:ATP
gptkbp:involves cellular energy homeostasis
gptkbp:locatedOnChromosome gptkb:chromosome_5p13.1
gptkbp:OMIM 602739
gptkbp:organism gptkb:Homo_sapiens
gptkbp:PDB gptkb:4CFE
gptkbp:phosphorylates multiple metabolic enzymes
gptkbp:RefSeq gptkb:NP_006243.2
gptkbp:regulates lipid metabolism
glucose uptake
fatty acid oxidation
gptkbp:UniProtID gptkb:Q13131
gptkbp:bfsParent gptkb:Prkaa1
gptkbp:bfsLayer 8