protein tyrosine phosphatase, non-receptor type 5

URI: https://gptkb.org/entity/protein_tyrosine_phosphatase,_non-receptor_type_5
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:alternativeName STEP
gptkbp:alternativeSplicing produces multiple isoforms
gptkbp:associatedWith neurological disorders
gptkbp:biologicalProcess gptkb:synaptic_plasticity
signal transduction
protein tyrosine phosphatase activity
gptkbp:encodedBy PTPN5 gene
gptkbp:enzymeCommissionNumber 3.1.3.48
gptkbp:expressedIn central nervous system
gptkbp:function dephosphorylation of tyrosine residues
regulation of MAP kinase pathway
gptkbp:gene gptkb:PTPN5
https://www.w3.org/2000/01/rdf-schema#label protein tyrosine phosphatase, non-receptor type 5
gptkbp:inhibitedBy MAPK signaling
gptkbp:involves gptkb:Alzheimer's_disease
gptkb:Huntington's_disease
schizophrenia
neurodegenerative diseases
learning and memory
gptkbp:locatedOnChromosome gptkb:chromosome_11q13
gptkbp:location brain
gptkbp:organism gptkb:Homo_sapiens
gptkbp:regulates gptkb:ERK1/2
gptkb:Fyn
gptkb:AMPA_receptor
gptkb:NMDA_receptor
phosphorylation-dependent
gptkbp:structure contains PTP domain
gptkbp:UniProtID gptkb:Q15256
gptkbp:bfsParent gptkb:PTPN5
gptkbp:bfsLayer 7