|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:AKT1_substrate_1
gptkb:Proline-rich_Akt_substrate_of_40_kDa
|
|
gptkbp:associatedWith
|
apoptosis
cell growth
insulin signaling
|
|
gptkbp:biologicalProcess
|
regulation of cell proliferation
regulation of autophagy
regulation of protein synthesis
|
|
gptkbp:encodedBy
|
gptkb:AKT1S1_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000123358
84335
|
|
gptkbp:fullName
|
gptkb:Proline-rich_AKT1_substrate_1
|
|
gptkbp:function
|
regulator of mTORC1 signaling
|
|
gptkbp:gene
|
gptkb:AKT1S1
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:21012
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PRAS40
|
|
gptkbp:inhibitedBy
|
gptkb:mTORC1
|
|
gptkbp:interactsWith
|
gptkb:14-3-3_proteins
gptkb:mTOR
gptkb:RAPTOR
|
|
gptkbp:locale
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:locatedOnChromosome
|
19q13.33
|
|
gptkbp:molecularWeight
|
40 kDa
|
|
gptkbp:OMIM
|
611497
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:6BCU
|
|
gptkbp:phosphorylates
|
gptkb:AKT1
Thr246
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
|
gptkbp:UniProtID
|
gptkb:Q96B36
|
|
gptkbp:bfsParent
|
gptkb:mTOR_pathway
|
|
gptkbp:bfsLayer
|
5
|