|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CORT
gptkb:pro-opiomelanocortin
OPMEL
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:discoveredBy
|
gptkb:Roger_Guillemin
|
|
gptkbp:encodes
|
pro-opiomelanocortin protein
|
|
gptkbp:Entrez_Gene_ID
|
5443
|
|
gptkbp:expressedIn
|
gptkb:pituitary_gland
hypothalamus
|
|
gptkbp:fullName
|
pro-opiomelanocortin gene
|
|
gptkbp:function
|
regulation of energy homeostasis
precursor for several peptide hormones
regulation of adrenal function
regulation of skin pigmentation
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:9201
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
POMC gene
|
|
gptkbp:length
|
241 amino acids
|
|
gptkbp:locatedOnChromosome
|
chromosome 2
2p23.3
|
|
gptkbp:mutationAssociatedWith
|
obesity
adrenal insufficiency
red hair pigmentation
|
|
gptkbp:OMIM
|
176830
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Pomc
|
|
gptkbp:pathway
|
gptkb:HPA_axis
melanocortin pathway
|
|
gptkbp:produces
|
gptkb:ACTH
gptkb:beta-endorphin
MSH
lipotropin
|
|
gptkbp:product
|
gptkb:pro-opiomelanocortin
|
|
gptkbp:referenceGenome
|
gptkb:GRCh38
|
|
gptkbp:regulates
|
gptkb:leptin
gptkb:corticotropin-releasing_hormone
|
|
gptkbp:symbol
|
gptkb:POMC
|
|
gptkbp:UniProtID
|
P01189
|
|
gptkbp:bfsParent
|
gptkb:alpha-MSH
gptkb:alpha-melanocyte-stimulating_hormone
gptkb:corticotroph
|
|
gptkbp:bfsLayer
|
7
|