|
gptkbp:instanceOf
|
polypeptide precursor
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
obesity
adrenal insufficiency
red hair phenotype
|
|
gptkbp:cleavage
|
prohormone convertases
|
|
gptkbp:discoveredBy
|
gptkb:Roger_Guillemin
|
|
gptkbp:encodedBy
|
gptkb:POMC_gene
|
|
gptkbp:expressedIn
|
gptkb:skin
gptkb:pituitary_gland
gptkb:placenta
hypothalamus
immune cells
|
|
gptkbp:foundIn
|
gptkb:adrenal_gland
|
|
gptkbp:function
|
modulation of immune response
regulation of pigmentation
hormone precursor
regulation of adrenal function
|
|
gptkbp:HGNC_ID
|
9201
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
pro-opiomelanocortin
|
|
gptkbp:locatedIn
|
chromosome 2
|
|
gptkbp:OMIM
|
176830
|
|
gptkbp:predecessor
|
gptkb:adrenocorticotropic_hormone
gptkb:beta-endorphin
met-enkephalin
corticotropin-like intermediate peptide
lipotropins
melanocyte-stimulating hormones
|
|
gptkbp:sequence
|
241 amino acids (human)
|
|
gptkbp:UniProtID
|
P01189
|
|
gptkbp:bfsParent
|
gptkb:alpha-MSH
gptkb:alpha-melanocyte-stimulating_hormone
gptkb:adrenocorticotropic_hormone
|
|
gptkbp:bfsLayer
|
7
|