|
gptkbp:instanceOf
|
hormone
|
|
gptkbp:abbreviation
|
gptkb:adrenocorticotropic_hormone
|
|
gptkbp:actsOn
|
melanocortin 2 receptor (MC2R)
|
|
gptkbp:aminoAcidLength
|
39
|
|
gptkbp:diagnosedBy
|
gptkb:Cushing's_syndrome
Addison's disease
secondary adrenal insufficiency
|
|
gptkbp:discoveredBy
|
Cushing, 1933
|
|
gptkbp:foundIn
|
humans
mammals
|
|
gptkbp:fullName
|
gptkb:adrenocorticotropic_hormone
|
|
gptkbp:gene
|
gptkb:POMC
|
|
gptkbp:halfLife
|
10 minutes
|
|
gptkbp:hasApprovedDrug
|
corticotropin injection
cosyntropin
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ACTH
|
|
gptkbp:medicalUse
|
infantile spasms
multiple sclerosis exacerbations
|
|
gptkbp:MeSH_ID
|
D000232
|
|
gptkbp:molecularWeight
|
4,540 Da
|
|
gptkbp:predecessor
|
pro-opiomelanocortin (POMC)
|
|
gptkbp:producedBy
|
anterior pituitary gland
|
|
gptkbp:promotion
|
adrenal cortex
|
|
gptkbp:PubChem_CID
|
CHEBI:27450
|
|
gptkbp:regulates
|
negative feedback by cortisol
corticotropin-releasing hormone (CRH)
|
|
gptkbp:secretedInResponseTo
|
stress
|
|
gptkbp:stimulatesProductionOf
|
gptkb:aldosterone
cortisol
|
|
gptkbp:structure
|
peptide
|
|
gptkbp:UniProtID
|
P01189
|
|
gptkbp:bfsParent
|
gptkb:steroid_hormone_biosynthesis
gptkb:opsoclonus-myoclonus_syndrome
gptkb:Medullary_thyroid_carcinoma
gptkb:adrenocorticotropic_hormone
gptkb:corticotroph
gptkb:PanNETs
|
|
gptkbp:bfsLayer
|
7
|